Metabolic

Anion gap (with albumin correction)

Classify metabolic acidosis as high or normal anion gap.

Version Standard

Inputs

Sodium(mmol/L)

Chloride(mmol/L)

Bicarbonate(mmol/L)

Albumin(g/dL)

Corrected anion gap (mmol/L)

Normal gap — if acidotic, consider GI or renal bicarbonate loss (hyperchloraemic acidosis).

Uncorrected anion gap 12 mmol/L

Formula

AG = Na − (Cl + HCO3); corrected AG = AG + 2.5 × (4.0 − albumin g/dL)

Archives of Internal Medicine · 1977

Demo content. Educational decision support only. Verify every dose, citation and recommendation against your national formulary and the primary source before clinical use.