Nephrology

eGFR (CKD-EPI 2021)

Estimate glomerular filtration rate from creatinine for CKD staging and drug dosing.

Version CKD-EPI 2021 (race-free)

Inputs

Divide µmol/L by 88.4 to convert to mg/dL.

eGFR (mL/min/1.73 m²)

89

CKD category G2. Review all renally cleared drugs and adjust doses.

  • Staging requires abnormality for ≥ 3 months plus albuminuria category.
  • Estimates are unreliable in AKI, extremes of muscle mass, pregnancy and amputation.

Formula

eGFR = 142 × min(Scr/κ,1)^α × max(Scr/κ,1)^-1.200 × 0.9938^age × 1.012 (if female); κ = 0.7 (F) / 0.9 (M)

New England Journal of Medicine · 2021

Demo content. Educational decision support only. Verify every dose, citation and recommendation against your national formulary and the primary source before clinical use.