American Heart Association / American Stroke Association · USA

AHA/ASA Guidelines for the Early Management of Acute Ischemic Stroke

Time-critical thrombolysis and thrombectomy windows, imaging selection and early secondary prevention.

2019Version 2019 updateNeurology

Key recommendations

  • AClass I

    IV thrombolysis is recommended within 4.5 h of symptom onset in eligible patients.

  • AClass I

    Mechanical thrombectomy within 6 h for anterior circulation large vessel occlusion; 6-24 h with perfusion selection.

  • BClass III/IIb

    Do not lower blood pressure aggressively unless > 220/120 mmHg or thrombolysis planned.

Applies to

Demo content. Educational decision support only. Verify every dose, citation and recommendation against your national formulary and the primary source before clinical use.