European Society of Cardiology · Europe

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

Four-pillar therapy for HFrEF, SGLT2 inhibitors across the ejection-fraction spectrum, congestion management.

2023Version 2021 with 2023 focused updateCardiology

Key recommendations

  • AClass I

    Start ARNI/ACEi, beta-blocker, MRA and SGLT2 inhibitor in all HFrEF patients as tolerated.

  • AClass I

    SGLT2 inhibitors are recommended in HFmrEF and HFpEF to reduce hospitalisation.

  • BClass I

    Use IV loop diuretics for congestion in acute heart failure.

Demo content. Educational decision support only. Verify every dose, citation and recommendation against your national formulary and the primary source before clinical use.